In Junethe U.ringmaster casino GAMBLING SITES THAT ACCEPT AMERICAN EXPRESS The bottom line is that USA residents can gamble legally at a large number of online gambling sites regardless of where they live. As always it will be important to look at the different laws in your area to see if online gambling is legal or illegal. All around the world, people want to know, "Is It Legal To Gamble Online?" On the global scale, this answer varies depending on the country. While this is an inconvenient truth, when you shrink it down to the national level it can get down right maddening. On the federal level, gambling online is perfectly legal, because of the lack of a law against it. It's possible to run afoul of state law (especially in extremely conservative states), but even there prosecution is extremely rare.